Nurofen Express: instruction
The medicine "Nurofen Express", the composition of whichincludes ibuprofen, belongs to the category of NSAID, a derivative of phenylpropionic acid. It has anti-inflammatory, antipyretic and analgesic effects. The mechanism of drug effect is based on the ability to slow down the synthesis of prostaglandins due to the blocking of cyclooxygenase enzymes. From the digestive system, the drug is absorbed quickly enough. The connection with proteins occurs by 90%. The drug is slowly transported into the joint cavities, accumulates in the synovial tissue, it forms larger concentrations than in the plasma. The drug is metabolized in the liver. The active substance is excreted in the urine and in an insignificant quantity with bile.
The medicine "Nurofen Express". Instructions. Indications
The drug is recommended for dental, head, rheumatic pain, migraine, algodismenorea. Indications include neuralgia, back pain, fever on the grounds of acute respiratory disease and influenza.
The drug "Nurofen Express." Instructions. Contraindications
Not recommended for cardiacinsufficiency of the expressed character, an arterial hypertensia in a serious current, lesions in organs GASTROINTESTINAL TRACT of the erosive or ulcerative type in an acute stage. The drug "Nurofen Express" instruction does not admit to the appointment with leukopenia, "aspirin" bronchial asthma, urticaria, caused by acid treatment of acetylsalicylic and other NSAIDs. Contraindications include hemorrhagic diathesis, the state of hypocoagulation, disorders in the activity of the kidneys or liver, pregnancy, lactation. Medication is not prescribed with hearing loss, in children (up to six years old), with pathologies in the vestibular apparatus, and also with intolerance of the components of the remedy.
The drug "Nurofen Express" (tablets) is prescribedon 200 mg to patients from twelve years three times-four times a day. If necessary, a quick clinical effect of the dose is increased to 400 mg three times a day. A day is not allowed to take more than 1200 mg. For children from 6 to 12 years of age, 200 mg is prescribed no more than four times. The drug is recommended for patients weighing more than twenty kilograms. Between reception of tablets the interval should be not less than six hours. Effervescent tablets are dissolved in a liquid (water), coated with a coating - swallowed whole and washed down.
The drug "Nurofen Express." Instructions. Side effects
When taking medication for two to three daysthere are almost no negative phenomena. With prolonged therapy, there is a risk of nausea, hepatitis, constipation, pancreatitis, reversible neuritis optic nerve. The drug can cause diplopia, flatulence,heartburn, a feeling of discomfort in the epigastrium, increased pressure, tachycardia. Some patients may experience leukopenia, allergic rhinitis, dyspnea, increased sweating during treatment. The drug can sometimes provoke cystitis, polyuria, nephrotic syndrome, anemia, agranulocytosis.